Group 1: Sean Phua, Elgin Patt, Neo Wei Hong, Liau Zheng En, Shawn Lim
i. What is the cause of the disease?
Ans: The reduction of white blood cells in the human body can be caused by cancer treatment like chemotherapy or radiation therapy as malignant cells overwhelm the bone marrow. Some illness like influenza or Hodgkin's lyphoma (a type of cancer that originates from lymphocytes) can also cause the reduction of white blood cells. Some medications like immunosuppresive drugs, such as sirolimus, mycophenolate mofetil, tacrolimus, and cyclosporine can also cause leukopenia. Leukopenia increases the chance of the patient getting an infection.
ii. How does the component of blood/ blood vessel affected in the disease?
Pseudoleukopenia can develop upon the onset of infection. The leukocytes are marginalized in the blood vessels so that they can scan for the site of infection. This means that even though there is increased white blood cell production, it will appear as though the white blood cell count is low from a blood sample, since the blood sample is of core blood and does not include the marginalized leukocytes.
iii. What is the function of the blood component/ structure in circulatory system?
White blood cells, or leukocytes, are cells of the immune system that defend the body against both infectious disease and foreign materials.
v. How will the absence of the blood component / structure affect the health of the patient?
With the decrease of white blood cells, the immune system becomes weak. With a weakened immune system, a person becomes much more vulnerable to even relatively minor infections.